QUADAS-3| Study design(s) targeted by the tool | Diagnostic test accuracy (DTA) studiesdiagnostic-test-accuracy-dta-studies |
|---|---|
| Additional details on designs | NA |
| Tool area | Health |
| Link to the tool | Get the QUADAS-3 tool |
Details | |
| Website | https://www.quadas.info |
| Primary publication | Whiting P, Tomlinson E, Rutjes A, et al. QUADAS-3: A Revised Tool for the Quality Assessment of Diagnostic Test Accuracy Studies. Ann Intern Med. 2026;doi:10.7326/annals-25-02104. |
| DOI | doi.org/10.7326/ANNALS-25-0494 |
| Guidance document | Get the QUADAS-3 guidance |
| Training | Training | Bristol Medical School: Population Health Sciences | University of Bristol |
| Language | English |
| Translations | None known – please contact us if you are aware of any translations that should be listed here. |
| Record last updated | 17/02/2026 |
Related tools and Publications | |
| Previous versions | |
| Updated versions | None |
| Related tools | |
| Evaluations | None known |
| Other publications | Tomlinson E, Yang B, Davenport CF, Rutjes AW, Mallett S, Whiting PF. Piloting QUADAS-3: a revised tool for the quality assessment of diagnostic accuracy studies. J Clin Epidemiol. 2025 Dec;188:111983. doi: 10.1016/j.jclinepi.2025.111983. Tomlinson E, Holmes J, Rutjes AWS, Davenport C, Leeflang M, Yang B, Mallett S, Whiting P. Developing a framework for assessing the applicability of the target condition in diagnostic research. J Clin Epidemiol. 2026 Feb;190:112059. doi: 10.1016/j.jclinepi.2025.112059. Epub 2025 Nov 15. PMID: 41248868. |
Key Criteria | |
| Focuses on risk of bias, or makes a distinction between items that assess risk of bias and other aspects of study quality | Yes |
| Offers a method to reach either a domain specific or overall assessment of risk of bias | Yes |
| Tool developed for use across topic areas (i.e. not developed for specific clinical area such as physiotherapy or dentistry) | Yes |
| Avoids recommending use of summary numerical quality scores | Yes |
