| Study design(s) targeted by the tool | Animal studiesanimal-studies |
|---|---|
| Additional details on designs | All aspects of animal models |
| Tool area | Animal studies |
| Link to the tool | Access the paper reporting the CRIME-Q tool |
Details | |
| Website | |
| Primary publication | Andersen, M.S., Kofoed, M.S., Paludan-Müller, A.S. et al. CRIME-Q - a unifying tool for critical appraisal of methodological (technical) quality, quality of reporting and risk of bias in animal research. BMC Med Res Methodol 24, 306 (2024) |
| DOI | https://doi.org/10.1186/s12874-024-02413-0 |
| Guidance document | |
| Training | None known – please contact us if you are aware of any training that should be listed here. |
| Language | English |
| Translations | None known – please contact us if you are aware of any translations that should be listed here. |
| Record last updated | 03/06/2026 |
Related tools and Publications | |
| Previous versions | None |
| Updated versions | None |
| Related tools | None |
| Evaluations | Paper reporting the tool article includes interrater reliability on 114 articles |
| Other publications | None known – please contact us if you are aware of any publications that should be listed here. |
Key Criteria | |
| Focuses on risk of bias, or makes a distinction between items that assess risk of bias and other aspects of study quality | No |
| Offers a method to reach either a domain specific or overall assessment of risk of bias | No |
| Tool developed for use across topic areas (i.e. not developed for specific clinical area such as physiotherapy or dentistry) | Yes |
| Avoids recommending use of summary numerical quality scores | Yes |