| Study design(s) targeted by the tool | Case seriescase-series |
|---|---|
| Additional details on designs | |
| Tool area | Health; Orphan medicines |
| Link to the tool | Access the paper reporting the COMPASS tool |
Details | |
| Website | |
| Primary publication | Picavet E, Cassiman D, Aertgeerts B, Simoens S. Development and validation of COMPASS: clinical evidence of orphan medicinal products - an assessment tool. Orphanet J Rare Dis. 2013;8:157. |
| DOI | doi:10.1186/1750-1172-8-157. |
| Guidance document | |
| Training | None known – please contact us if you are aware of any training that should be listed here. |
| Language | English |
| Translations | None known – please contact us if you are aware of any translations that should be listed here. |
| Record last updated | 03/06/2026 |
Related tools and Publications | |
| Previous versions | None |
| Updated versions | None |
| Related tools | None |
| Evaluations | None known – please contact us if you are aware of any evaluations that should be listed here. |
| Other publications | None known – please contact us if you are aware of any publications that should be listed here. |
Key Criteria | |
| Focuses on risk of bias, or makes a distinction between items that assess risk of bias and other aspects of study quality | Yes |
| Offers a method to reach either a domain specific or overall assessment of risk of bias | No |
| Tool developed for use across topic areas (i.e. not developed for specific clinical area such as physiotherapy or dentistry) | No |
| Avoids recommending use of summary numerical quality scores | Yes |
