Library of risk of bias tools

AGREE

Study design(s) targeted by the tool Guidelinesguidelines
Additional details on designs NA
Tool area Health
Link to the tool Get the AGREE tool

Details

Website https://www.agreetrust.org/resource-centre/the-original-agree-instrument/
Primary publication AGREE Collaboration. Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project. Quality and Safety in Health Care 2003;12(1)
DOI 10.1136/qhc.12.1.18
Guidance document
Training

None known – please contact us if you are aware of any evaluations that should be listed here.

Language English
Translations

Many – available on AGREE website.

Record last updated 03/06/2026

Related tools and Publications

Previous versions

None

Updated versions

AGREE II

Related tools

variety of tools have been developed to assist in the development, reporting and evaluation of practice guidelines

Evaluations

None known – please contact us if you are aware of any evaluations that should be listed here

Other publications

Brouwers MC, Spithoff K, Lavis J, Kho ME, Makarski J, Flórez ID, What to Do With All The AGREEs? The AGREE Portfolio of Tools to Support The Guideline Enterprise, Journal of Clinical Epidemiology (2020), doi: https://doi.org/10.1016/j.jclinepi.2020.05.025.

Key Criteria

Focuses on risk of bias, or makes a distinction between items that assess risk of bias and other aspects of study quality No
Offers a method to reach either a domain specific or overall assessment of risk of bias Yes
Tool developed for use across topic areas (i.e. not developed for specific clinical area such as physiotherapy or dentistry) Yes
Avoids recommending use of summary numerical quality scores No