The following videos, delivered by Julian Higgins (lead author of the tool), provide an introduction to each of the RoB 2 domains:
Domain 1 – Bias arising from the randomization process
Domain 2 – Bias due to deviations from intended interventions
Domain 3 – Bias due to missing outcome data
Domain 4 – Bias in measurement of the outcome
Domain 5 – Bias in selection of the reported results